TY - DATA T1 - Data underlying the publication: Histones and histone variant families in prokaryotes PY - 2024/07/16 AU - Samuel Schwab AU - Yimin Hu AU - Bert van Erp AU - Marc K. M. Cajili AU - Marcus D. Hartmann AU - Birte Hernandez Alvarez AU - Vikram Alva AU - Aimee L. Boyle AU - Remus T. Dame UR - DO - 10.4121/d268a6a9-2fc5-46aa-a236-0ca3d3f7ed75.v1 KW - Prokaryotic histones KW - AlphaFold2 KW - Bridging histones KW - a3 histones KW - Hypernucleosome KW - Novel histones KW - Archaeal histones KW - Bacterial histones KW - chromatin KW - genome organization N2 -
The research objective was to make an overview of histones in prokaryotes and to categorize these histones. We have categorized these histones by predicting their monomeric and multimeric structures with AlphaFold2. Histones with similar predicted quaternary structures or with additional domains were categorized as one group. We provide functional insight into these histones from these predicted structures and by generating HMM profiles to find strongly conserved residues. The dataset contains the predicted structures shown in the article, the HMM profiles of all histone categories, and the list of prokaryotic histones.
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