%0 Generic
%A Schwab, Samuel
%A Hu, Yimin
%A van Erp, Bert
%A Cajili, Marc K. M.
%A Hartmann, Marcus D.
%A Alvarez, Birte Hernandez
%A Alva, Vikram
%A Boyle, Aimee L.
%A Dame, Remus T.
%D 2024
%T Data underlying the publication: Histones and histone variant families in prokaryotes
%U 
%R 10.4121/d268a6a9-2fc5-46aa-a236-0ca3d3f7ed75.v2
%K Prokaryotic histones
%K AlphaFold2
%K Bridging histones
%K a3 histones
%K Hypernucleosome
%K Novel histones
%K Archaeal histones
%K Bacterial histones
%K chromatin
%K genome organization
%X <p>The research objective was to make an overview of histones in prokaryotes and to categorize these histones. We have categorized these histones by predicting their monomeric and multimeric structures with AlphaFold2. Histones with similar predicted quaternary structures or with additional domains were categorized as one group. We provide functional insight into these histones from these predicted structures and by generating HMM profiles to find strongly conserved residues. The dataset contains the predicted structures shown in the article, the HMM profiles of all histone categories, and the list of prokaryotic histones.</p>
%I 4TU.ResearchData