%0 Generic %A Zhou, Jie %D 2021 %T Data underlying the research of: A Comprehensive Genome-wide Analysis of Long Non-coding RNA and mRNA Expression Profiles of JAK2V617F-positive Classical Myeloproliferative Neoplasms %U https://data.4tu.nl/articles/dataset/Data_underlying_the_research_of_A_Comprehensive_Genome-wide_Analysis_of_Long_Non-coding_RNA_and_mRNA_Expression_Profiles_of_JAK2V617F-positive_Classical_Myeloproliferative_Neoplasms/15060171/1 %R 10.4121/15060171.v1 %K classical myeloproliferative neoplasms (cMPNs) %K hematologic malignancy patients %X
Aberrant expression of long non-coding RNAs (lncRNAs) is involved in the progression of myeloid neoplasms, but the role of lncRNAs in classical myeloproliferative neoplasms (cMPNs) remains unclear. The present study was conducted to clarify the expression and regulation patterns of lncRNAs in cMPNs, and to explore new potential carcinogenic factor of cMPNs.Bioinformatics analysis of microarray data and qRT-PCR validation were performed to study the expression and regulation signature of differentially expressed lncRNAs (DELs) and related genes (DEGs) in cMPNs.
%I 4TU.ResearchData