cff-version: 1.2.0
abstract: "<p>Single-molecule imaging data files of DNA loop extrusion by yeast condensin on DNA with Rap1 protein arrays. Both whole fields of view (FOVs) and single cropped DNA molecules are deposited.</p><p><br></p><p>The dataset is part of a cell biology and biophysics study of how the process of DNA loop extrusion by condensin interacts with multiple roadblocks on DNA. We found that arrays of proteins may stall DNA loop extrusion dependent on their length and density, both in vivo and in vitro.</p><p><br></p><p>The data was generated using single-molecule HILO fluorescence microscopy on DNA (intercalating fluorophores) and fluorescently labeled proteins (Rap1 and LacI proteins). This subset of data gives a representative overview of the data that was obtained for the related journal article. It serves as a demonstration of the type of data and the type of events that were analyzed.</p><p><br></p><p>The README file contains more specific information on the imaging and file structure/naming.</p>"
authors:
  - family-names: Analikwu
    given-names: Brian
    orcid: "https://orcid.org/0000-0003-0158-1989"
  - family-names: Deshayes
    given-names: Alice
    orcid: "https://orcid.org/0000-0002-3542-7413"
  - family-names: van der Torre
    given-names: Jaco
    orcid: "https://orcid.org/0000-0002-5405-3824"
  - family-names: Guérin
    given-names: Thomas
    orcid: "https://orcid.org/0000-0002-2336-315X"
  - family-names: Katan
    given-names: Allard
    orcid: "https://orcid.org/0000-0002-7185-6274"
  - family-names: Benéut
    given-names: Claire
    orcid: "https://orcid.org/0009-0009-4087-9658"
  - family-names: Barth
    given-names: Roman 
  - family-names: Phipps
    given-names: Jamie
    orcid: "https://orcid.org/0000-0002-5851-4640"
  - family-names: Scolari
    given-names: Vittore
    orcid: "https://orcid.org/0000-0003-3490-0579"
  - family-names: Veaute
    given-names: Xavier
    orcid: "https://orcid.org/0000-0003-4868-247X"
title: "Single-molecule microscopy data related to &#34;Telomeres stall DNA loop extrusion by condensin&#34;"
keywords:
version: 1
identifiers:
  - type: doi
    value: 10.4121/4dae22e3-0eed-4f9b-8c47-3d4555010e3e.v1
license: CC BY-NC-SA 4.0
date-released: 2025-06-20