cff-version: 1.2.0
abstract: "<p>Datasets for the publication "Unjamming transitions in cancer cell spheroids are linked to EMT-dependent cell-matrix interactions", to be submitted.</p><p>Datasets include the raw tif files of 3D spheroid invasion assays of A549 and MV3 spheroids embedded in collagen (2.4 and 8 mg/mL) and gelMA (30 and 50 mg/mL). This include time-series bright-field imaging for 24 hrs (MV3) and 72 hrs (A549) at one hour interval. The spheroids were treated with exogenous TGF-β and broad spectrum MMP-inhibitor and imaged under same conditions.</p><p>Datasets include MATLAB/.m codes to analyze the spheroid images for effective spheroid radius, number of disseminated cells, rate of invasion and protrusion length. Additionally, MATLAB codes/.m to plot figures are also included within each respective condition. Raw data for supplementary data is also provided as images, excel files and MATLAB scripts.</p>"
authors:
  - family-names: van der Net
    given-names: Anouk
  - family-names: Rahman
    given-names: Zaid 
    orcid: "https://orcid.org/0000-0003-1154-2764"
  - family-names: Deep Bordoloi
    given-names: Ankur 
  - family-names: Muntz
    given-names: Iain
    orcid: "https://orcid.org/0000-0002-8434-8316"
  - family-names: ten Dijke 
    given-names: Peter
  - family-names: Boukany
    given-names: Pouyan
    orcid: "https://orcid.org/0000-0002-2262-5795"
  - family-names: Koenderink
    given-names: G.H. (Gijsje)
    orcid: "https://orcid.org/0000-0002-7823-8807"
title: "Data underlying the publication: Unjamming transitions in cancer cell spheroids are linked to EMT-dependent cell-matrix interactions"
keywords:
version: 1
identifiers:
  - type: doi
    value: 10.4121/3af75b5a-db30-419c-97ab-a5f632812a6c.v1
license: CC BY 4.0
date-released: 2024-04-10