TIPE2, RELA(NF-κb p65), TNF-α, IL-10, IL-6, and IL-1β mRNA expression in peripheral blood mononuclear cells from patients with psoriasis vulgaris

doi:10.4121/21836289.v1
The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/21836289
Datacite citation style:
Hua Hu; Xiuyu Fu; Dandan Fu; Jialin Li; Xinyu Zhang et. al. (2023): TIPE2, RELA(NF-κb p65), TNF-α, IL-10, IL-6, and IL-1β mRNA expression in peripheral blood mononuclear cells from patients with psoriasis vulgaris. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/21836289.v1
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Dataset
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October 2021 to March 2022

 The present study intended to detect the expression levels of TIPE2 mRNA in the peripheral blood mononuclear cells (PBMCs) of psoriasis vulgaris patients and analyze the correlation between TIPE2 and other inflammatory cytokines variations in psoriasis vulgaris pathogenesis.   

Thirty-three patients with psoriasis vulgaris and 31 healthy volunteers were enrolled in the study. The mRNA expression of TIPE2, RELA(NF-κb p65), TNF-α, IL-10, IL-6, and IL-1β in PBMCs was determined using RT-qPCR. The severity of psoriasis vulgaris was determined according to the PASI(psoriasis area and severity index) score.

history
  • 2023-01-09 first online, published, posted
publisher
4TU.ResearchData
format
xlsx
funding
  • Science and Technology Research Project of Henan Province (No. 212102310184)
  • Joint Construction Project of Health Commission of Henan Province (NO LHGJ20220597)
organizations
Department of Dermatology, The First Affiliated Hospital of Xinxiang Medical University
Xinxiang Key Laboratory of Psoriasis and Skin Tumor Research
Department of Immunology, School of Basic Medical Sciences, Xinxiang Medical University
Xinxiang Engineering Technology Research Center of immune checkpoint drug for Liver-Intestinal Tumors

DATA

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