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DOI: 10.4121/77eb9e56-3208-413e-b90f-9f15366e96ae

Sherlock, Brock; Boon, Marko (2025): Discrete Event Simulation for Queuing Model of Intracellular GLUT4 Translocation. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/77eb9e56-3208-413e-b90f-9f15366e96ae.v1

Categories

• Applied Mathematics
• Mathematical Sciences

Keywords

Discrete event simulation (DES) GLUT4 Trafficking intracellular transport queuing theory

Licence

EUPL-1.2

Interoperability

• RO-Crate Metadata

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by Brock Sherlock , Marko Boon

Discrete Event Simulation implemented in Java OpenJDK 19.0.1 for a mechanistic model of intracellular GLUT4 trafficking. The model associated with the simulation was used to assess possible mechanisms of GLUT4 sequestration and release in response to insulin. Specifically, this model implements a mechanism for the activity of fusion sites to be insulin-dependent. Simulation outputs were compared to experimental data and model parameters estimated to assess the quality of this mechanism as an explanation of observed dynamics. Source code is provided as well as executable .jar files.

History

• 2025-11-17 first online, published, posted

Publisher

4TU.ResearchData

Format

code/.java executable/.jar sampleOutput/.csv

References

• https://link.springer.com/article/10.1007/s11538-024-01331-y
• https://link.springer.com/article/10.1007/s11538-024-01331-y

Organizations

TU Eindhoven, Department of Mathematics and Computer Science;
UNSW Sydney, School of Mathematics and Statistics