Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals.
DOI:10.4121/collection:ONE_Flow
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DOI: 10.4121/c.5065355
DOI: 10.4121/c.5065355
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(2019): Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals. Version 1. 4TU.ResearchData. collection. https://doi.org/10.4121/collection:ONE_Flow
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The ONE-FLOW project translates a ‘vertical hierarchy’ of chemical multistep synthesis with its complex machinery into a self-organising ‘horizontal hierarchy’ of a compartmentalized flow reactor system – a biomimetic digital flow cascade machinery with just one reactor passage. To keep the horizontal hierarchy manageable, orthogonality needs to be increased among the different consecutive reactions.
History
- 2021-12-30 first online
- 2019-04-10 published, posted
- 2020-07-17 revised